Oncology

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5.5 people die from cancer every minute in China alone and every year there are more than 4.5 million new cases diagnosed.

Infigratinib (BGJ398)

Oncology

Infigratinib (BGJ398) is an investigational, orally administered FGFR1-3 tyrosine kinase inhibitor in development for the treatment of patients with FGFR-driven diseases, including cholangiocarcinoma (bile duct cancer) and urothelial carcinoma (bladder cancer).

Phase 3

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BBP-398

Oncology

BBP-398 is an allosteric SHP2 inhibitor designed to inhibit wild-type SHP2, offering the potential to treat the variety of tumors that rely on SHP2 activity for proliferation and survival. SHP2 binds to RTKs and immune checkpoint receptors to regulate their signaling.

Phase 1b

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